A clear look at every active in the UltraLift serum and the VitaLock beauty nutrients, what each one is commonly studied for, and links to the research behind the claims.
The serum's main active is a synthetic dipeptide whose ingredient name is Dipeptide Diaminobutyroyl Benzylamide Diacetate, marketed as SYN-AKE. It belongs to the "neuromodulating" peptide family, alongside ingredients like Argireline, that aim to soften the look of expression lines by reducing the appearance of repeated facial-muscle movement.
In a clinical study of a peptide complex on women over 40, topical peptides significantly improved the look of facial wrinkles and supported skin's structural proteins. The appeal of SYN-AKE specifically is that it targets dynamic lines — the crow's-feet and forehead creases driven by expression — in a non-invasive, reversible way, making it a popular topical alternative to injectables for everyday use.
Sodium hyaluronate is the salt form of hyaluronic acid (HA), the moisture molecule your skin makes naturally. It is a humectant valued because it can hold many times its weight in water, and the salt form is smaller and more stable than pure HA, which helps it sit well in a serum.
Topical HA is one of the best-evidenced hydration ingredients in skincare. In a multicenter evaluation, a hyaluronic acid serum significantly improved the look of fine lines, texture, and hydration over eight weeks. Separate studies of advanced HA formulations reported meaningful gains in skin hydration, firmness, and the appearance of wrinkle depth. The mechanism is intuitive: hydrated skin looks plumper, so lines look softer. That is why HA works best when it is treated as a daily hydration step, not as a one-time rescue.
Vitamin C, as L-ascorbic acid, is among the most-researched antioxidants in dermatology. It plays a documented role in the skin's collagen-building pathway and helps defend against the daily oxidative stress that accelerates visible aging.
One often-cited clinical study showed that topically applied vitamin C raised the messenger-RNA levels of collagens I and III in the human dermis — direct evidence of its involvement in the collagen pathway. Reviews of topical vitamin C consistently describe tone-brightening, more even-looking tone, and support for a firmer, smoother appearance with consistent use. It also helps replenish vitamin E, which is why the two are paired in the serum. Freshness, storage, and sunscreen matter just as much as the label claim.
Tocopheryl acetate is a stable, skin-comforting form of vitamin E, a fat-soluble antioxidant naturally present in the skin's barrier. In formulas it helps defend against oxidative stress and helps skin feel softer and hold moisture.
Vitamin E is best understood as a supporting player. Dermatology reviews point out that vitamin C is the primary replenisher of vitamin E and that the two work synergistically in protecting skin against oxidative damage — which is exactly why a well-built serum includes both rather than either alone. On its own, vitamin E contributes to a smooth, conditioned feel and a healthy-looking barrier. Freshness, storage, and sunscreen matter just as much as the label claim.
Glycerin is one of the oldest and most well-known humectants in all of skincare. It draws water into the outer skin layers and helps hold it there, keeping the complexion supple and dewy rather than tight, flaky, or dry.
While glycerin rarely gets headlines, it is a quietly useful ingredient: it improves the immediate feel and look of skin, supports the moisture barrier, and helps other actives perform in a comfortable, well-hydrated environment. Its excellent safety and tolerability profile is part of why it appears in formulas for even the most sensitive skin.
The optional VitaLock capsule completes the system with nutrients often linked with skin, hair, and nail support. A dermatology review of these nutrients is honest that the evidence for beauty supplements is mixed and still not fully settled — they are best seen as nutritional support, not a guaranteed result.
| Nutrient | Associated Support |
|---|---|
| Biotin | Hair, skin & nail support |
| Niacinamide | Skin radiance support |
| Vitamin B6 | Normal skin appearance |
| Zinc | Healthy-looking skin |
| Horsetail Extract | Botanical silica beauty support |
Ingredient research describes individual molecules, often in specific formulations and concentrations, and much of it is early-stage. That a peptide or vitamin performs well in a study cannot guarantee a particular result from any finished product for any individual. We link the research so you can read it yourself, and we describe these as appearance-support ingredients — which is what the evidence supports.
Support firmer, smoother, more hydrated-looking skin with a 60-day money-back guarantee and free bonus guides.
Visit the Official Synevra UltraLift WebsiteOfficial website only · 60-day money-back guarantee · Free bonus eBooks